https://repositorio.ufba.br/handle/ri/12746
Tipo: | Artigo de Periódico |
Título: | Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline |
Título(s) alternativo(s): | Australian Journal of Chemistry |
Autor(es): | Silva, Michelli M. Bergamasco, Juliana Lira, Simone Possedente de Lopes, Norberto Peporine Hajdu, Eduardo Peixinho, Solange Berlinck, Roberto Gomes de Souza |
Autor(es): | Silva, Michelli M. Bergamasco, Juliana Lira, Simone Possedente de Lopes, Norberto Peporine Hajdu, Eduardo Peixinho, Solange Berlinck, Roberto Gomes de Souza |
Abstract: | In order to investigate the chemical profile of 14 specimens of Aplysina spp. marine sponges, we have developed a method based on LC-PDA-MS for the detection of bromotyrosine-derived metabolites. The method enabled the dereplication of three distinct chemotypes of bromotyrosine-derived compounds based on UV absorptions, which were further refined by electrospray ionization-mass spectrometry analysis of the brominated quasi-molecular ion clusters. This procedure led to either a single compound assignment, or a maximum of two possible isobaric compounds. The dereplication study indicated that the chemical profile of the 14 specimens of Aplysina spp. analyzed presented practically the same dibromotyrosine-derived compounds. The results obtained suggested a possible biogenetic pathway for the formation of dibromotyrosine-derived compounds of wide occurrence in Verongida sponges. |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/12746 |
Data do documento: | 2010 |
Aparece nas coleções: | Artigo Publicado em Periódico (Química) |
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Michelli M. Silva.pdf Restricted Access | 512 kB | Adobe PDF | Visualizar/Abrir Solicitar uma cópia |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.