Campo DC | Valor | Idioma |
dc.contributor.author | Barreto, Mauricio Lima | - |
dc.contributor.author | Farenzena, G. G. | - |
dc.contributor.author | Fiaccone, R. L. | - |
dc.contributor.author | Santos, L. M. P. | - |
dc.contributor.author | Assis, Ana Marlucia de Oliveira | - |
dc.contributor.author | Araújo, M. P. N. | - |
dc.contributor.author | Santos, P. A. B. | - |
dc.creator | Barreto, Mauricio Lima | - |
dc.creator | Farenzena, G. G. | - |
dc.creator | Fiaccone, R. L. | - |
dc.creator | Santos, L. M. P. | - |
dc.creator | Assis, Ana Marlucia de Oliveira | - |
dc.creator | Araújo, M. P. N. | - |
dc.creator | Santos, P. A. B. | - |
dc.date.accessioned | 2013-09-17T17:43:36Z | - |
dc.date.available | 2013-09-17T17:43:36Z | - |
dc.date.issued | 1994 | - |
dc.identifier.issn | 0140-6736 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/12969 | - |
dc.description | Texto completo. Acesso restrito. p. 228–231 | pt_BR |
dc.description.abstract | A beneficial effect of periodic vitamin A supplementation on childhood mortality has been demonstrated, but the effect on morbidity is less clear. We investigated the effect of vitamin A supplementation on diarrhoea and acute lower-respiratory-tract infections (ALRI) in children from northeastern Brazil in a randomised, double-blind, placebo-controlled community trial.
1240 children aged 6-48 months were assigned vitamin A or placebo every 4 months for 1 year. They were followed up at home three times a week, and data about the occurrence and severity of diarrhoea and ALRI were collected. Any child with cough and respiratory rate above 40 breaths per min was visited by a paediatrician. The overall incidence of diarrhoea episodes was significantly lower in the vitamin-A-supplemented group than in the placebo group (18·42 vs 19·58 × 10-3 child-days; rate ratio 0·94 [95% Cl 0·90-0·9 8]). The benefit of supplementation was greater as regards severe episodes of diarrhoea; the incidence was 20% lower in the vitamin A group than in the placebo group (rate ratio 0·80 [0·65-0·98]). With the standard definition of diarrhoea (≥3 liquid or semi-liquid stools in 24 h) the effect of vitamin A on mean daily prevalence did not reach significance, but as the definition of diarrhoea was made more stringent (increasing number of stools per day), a significant benefit became apparent, reaching for diarrhoea with 6 or more liquid or semi-liquid stools in 24 h a 23% lower prevalence. We found no effect of vitamin A supplementation on the incidence of ALRI.
The reduction in severity of diarrhoea may be the most important factor in the lowering of mortality by vitamin A supplementation. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Lancet | pt_BR |
dc.source | http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/S0140-6736(94)92998-X | pt_BR |
dc.title | Effect of vitamin A supplementation on diarrhoea and acute lower-respiratory-tract infections in young children in Brazil | pt_BR |
dc.title.alternative | Lancet | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | Salvador | pt_BR |
dc.identifier.number | v. 344, n. 8917 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico Estrangeiro (ISC)
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