Campo DC | Valor | Idioma |
dc.contributor.author | Neri, Daniela Almeida | - |
dc.contributor.author | Mattos, Ângela Peixoto de | - |
dc.contributor.author | Ribeiro, Tereza Cristina Medrado | - |
dc.contributor.author | Mendes, Patrícia Silva de Almeida | - |
dc.contributor.author | Valois, Sandra Santos | - |
dc.contributor.author | Ribeiro Jr., Hugo da Costa | - |
dc.creator | Neri, Daniela Almeida | - |
dc.creator | Mattos, Ângela Peixoto de | - |
dc.creator | Ribeiro, Tereza Cristina Medrado | - |
dc.creator | Mendes, Patrícia Silva de Almeida | - |
dc.creator | Valois, Sandra Santos | - |
dc.creator | Ribeiro Jr., Hugo da Costa | - |
dc.date.accessioned | 2013-10-30T16:37:06Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0271-5317 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/13325 | - |
dc.description | Texto completo: acesso restrito. p. 244-247 | pt_BR |
dc.description.abstract | Nucleotides have been identified as conditionally essential nutrients. As prevention studies, conducted with nucleotide-supplemented formula, have shown statistically significant decrease in the risk of diarrhea, we tested the hypothesis that the consumption of nucleotide-supplemented formula during an acute diarrhea episode is associated with therapeutic effects in the treatment of infants with acute diarrhea and dehydration. A randomized, double-blind, controlled clinical trial was conducted in which patients were randomly assigned to 1 of 2 treatment groups. The “test” group consumed a nucleotide-supplemented infant formula and the “control” group consumed a nonsupplemented formula. Infants were accommodated in a metabolic unit where body weight, and all intakes and outputs were recorded at 24-hour intervals during hospitalization. Laboratory parameters including blood gases and electrolytes were monitored during hospitalization. Eighty-one male infants ranging in age from older than 1 month and younger than 1 year, with acute non-cholera diarrhea and dehydration were studied. Primary outcomes were stool output and duration of diarrhea and did not differ significantly between the groups, with a stool output of 304.2 (SD 254.0) vs 350.3 (SD 269.1) g/kg and a duration of diarrhea of 83.3 (SD 44.5) vs 88.8 (SD 46.6) for the test and control groups, respectively. Anemia was highly prevalent and breast-feeding practice was not frequent in both groups. The average energy intake and weight gain were similar in the 2 groups. This study demonstrated that nucleotide supplementation of infant formula during episodes of acute diarrhea has no therapeutic advantage compared to conventional infant formula. | pt_BR |
dc.language.iso | en | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://dx.doi.org/10.1016/j.nutres.2009.03.004 | pt_BR |
dc.subject | Acute diarrhea | pt_BR |
dc.subject | Children | pt_BR |
dc.subject | Nucleotides | pt_BR |
dc.subject | Nutritional management | pt_BR |
dc.subject | Infant formula | pt_BR |
dc.title | Lack of effect of nucleotide-supplemented infant formula on the management of acute diarrhea in infants | pt_BR |
dc.title.alternative | Nutrition Research | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 29, n. 4 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
dc.publisher.country | Brasil | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina)
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