https://repositorio.ufba.br/handle/ri/14480
Tipo: | Artigo de Periódico |
Título: | Clinical, anthropometric and upper airway anatomic characteristics of obese patients with obstructive sleep apnea syndrome |
Título(s) alternativo(s): | Respiration |
Autor(es): | Hora, Francisco Nápolis, Lara Maris Daltro, Carla Hilário da Cunha Kodaira, Sérgio Keidi Tufik, Sérgio Togeiro, Sônia Maria Nery, Luiz Eduardo |
Autor(es): | Hora, Francisco Nápolis, Lara Maris Daltro, Carla Hilário da Cunha Kodaira, Sérgio Keidi Tufik, Sérgio Togeiro, Sônia Maria Nery, Luiz Eduardo |
Abstract: | Background: Obese subjects are at increased risk of developing obstructive sleep apnea syndrome (OSAS). However, the individual role of local (i.e., upper airway-related) and general (clinical and whole-body anthropometric) characteristics in determining OSAS in obese patients is still controversial. Objectives: To contrast the clinical, anthropometric and upper airway anatomical features of obese subjects presenting or not presenting with OSAS. Methods: Thirty-seven obese (BMI ≥30 kg/m2) males with OSAS and 14 age- and gender-matched obese controls underwent clinical and anthropometric (BMI, waist-to-hip ratio and neck circumference) evaluation. In a subgroup of subjects (18 and 11 subjects, respectively), magnetic resonance imaging (MRI) during wakefulness was used to study the upper airway anatomy. Results: OSAS patients showed significantly higher BMI, waist-to-hip ratio and neck circumference as compared to controls (p < 0.05). They also referred to nonrepairing sleep, impaired attention, and previous car accidents more frequently (p < 0.05). The transversal diameter of the airways (TDAW) at the retroglossal level by MRI was found to be an independent predictor of the presence and severity of OSAS (p < 0.05). Parapharyngeal fat increase, however, was not related to OSAS. A TDAW >12 mm was especially useful to rule out severe OSAS (apnea-hypopnea index >30, negative predictive value = 88.9%, likelihood ratio for a negative test result = 0.19). Conclusions: MRI of the upper airway can be used in association with clinical and anthropometric data to identify obese males at increased risk of OSAS. |
Palavras-chave: | Magnetic resonance imaging Obstructive sleep apnea Obesity Sleep |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/14480 |
Data do documento: | 2007 |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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10.1159-000097790.pdf | 259,04 kB | Adobe PDF | Visualizar/Abrir |
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