Campo DC | Valor | Idioma |
dc.contributor.author | Salles, Fernanda | - |
dc.contributor.author | Bacellar, Andrea | - |
dc.contributor.author | Amorim, Mirla | - |
dc.contributor.author | Orge, Glória | - |
dc.contributor.author | Sundberg, Michael A. | - |
dc.contributor.author | Lima, Márcia | - |
dc.contributor.author | Santos, Silvane Maria Braga | - |
dc.contributor.author | Porto, Maria Aurélia da Fonseca | - |
dc.contributor.author | Carvalho Filho, Edgar Marcelino de | - |
dc.creator | Salles, Fernanda | - |
dc.creator | Bacellar, Andrea | - |
dc.creator | Amorim, Mirla | - |
dc.creator | Orge, Glória | - |
dc.creator | Sundberg, Michael A. | - |
dc.creator | Lima, Márcia | - |
dc.creator | Santos, Silvane Maria Braga | - |
dc.creator | Porto, Maria Aurélia da Fonseca | - |
dc.creator | Carvalho Filho, Edgar Marcelino de | - |
dc.date.accessioned | 2014-06-05T16:30:52Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0035-9203 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/15057 | - |
dc.description | Texto completo: acesso restrito. p. 526-529 | pt_BR |
dc.description.abstract | Background Human T cell lymphotropic virus type 1 (HTLV-1) infection has been associated with recurrent and disseminated strongyloidiasis and adult T cell leukemia/lymphoma (ATLL).
Methods We compared immunological aspects and markers for ATLL in HTLV-1 patients with or without strongyloidiasis, and evaluated the influence of Strongyloides stercoralis treatment on the immune response and clinical outcomes of HTLV-1 infection.
Results Levels of TNFα and IFNγ were lower in patients coinfected with HTLV-1 and S. stercoralis than in patients with HTLV-1 only (p < 0.05), and there was an increase in TNFα levels after anthelmintic treatment. Levels of sIL-2R were higher in patients with HTLV-1 coinfected with S. stercoralis and anthelmintic treatment decreased sIL-2R levels (p < 0.05). The one patient who developed ATLL was coinfected with S. stercoralis.
Conclusion These data show that helminthic infection has a modulatory role in HTLV-1 infection and that S. stercoralis may be a cofactor in the development of ATLL. | pt_BR |
dc.language.iso | en | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://dx.doi.org/10.1093/trstmh/trt052 | pt_BR |
dc.subject | HTLV-1 | pt_BR |
dc.subject | Strongyloides stercoralis | pt_BR |
dc.subject | Leukemia | pt_BR |
dc.subject | ATLL | pt_BR |
dc.subject | Interleukin-2 receptor | pt_BR |
dc.subject | sIL-2R | pt_BR |
dc.subject | Human T-lymphotropic virus 1 | pt_BR |
dc.subject | Leukemia-Lymphoma, Adult T-Cell | pt_BR |
dc.title | Treatment of strongyloidiasis in HTLV-1 and Strongyloides stercoralis coinfected patients is associated with increased TNFα and decreased soluble IL2 receptor levels | pt_BR |
dc.title.alternative | Transactions of The Royal Society of Tropical Medicine and Hygiene | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 107, n. 8 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina)
|