https://repositorio.ufba.br/handle/ri/15949
Tipo: | Artigo de Periódico |
Título: | Clinical manifestations associated with HTLV type I infection: a cross-sectional study |
Título(s) alternativo(s): | AIDS Research and Human Retroviruses |
Autor(es): | Caskey, Marina F. Morgan, Daniel J. Porto, Maria Aurélia da Fonseca Giozza, Silvana P. Muniz, André Luís Nunes Orge, Glória O. Travassos, Maria J. Barrón, Yolanda Carvalho Filho, Edgar Marcelino de Glesby, Marshall J. |
Autor(es): | Caskey, Marina F. Morgan, Daniel J. Porto, Maria Aurélia da Fonseca Giozza, Silvana P. Muniz, André Luís Nunes Orge, Glória O. Travassos, Maria J. Barrón, Yolanda Carvalho Filho, Edgar Marcelino de Glesby, Marshall J. |
Abstract: | Human T-lymphotropic virus type I (HTLV-I) causes HTLV-I-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia in a small percentage of infected individuals. HTLV-I infection is increasingly associated with clinical manifestations. To determine the prevalence of clinical manifestations in HTLV-I infected individuals, we conducted a cross-sectional study of 115 HTLV-I-infected blood donors without myelopathy and 115 age- and sex-matched seronegative controls. Subjects answered a standardized questionnaire and underwent physical examination. Compared with controls, HTLV-I-infected subjects were more likely to report arm or leg weakness (OR = 3.8, 95% CI: 1.4–10.2; OR = 4.0, 95% CI: 1.6–9.8, respectively), hand or foot numbness (OR = 2.1, 95% CI: 1.1–3.9; OR = 4.8, 95% CI: 2.0–11.7, respectively), arthralgia (OR = 3.3, 95% CI: 1.7–6.4), nocturia (OR = 2.7, 95% CI: 1.04–6.8), erectile dysfunction (OR = 4.0, 95% CI: 1.6–9.8), and to have gingivitis (OR = 3.8, 95% CI: 1.8–7.9), periodontitis (OR = 10.0, 95% CI: 2.3–42.8), and dry oral mucosa (OR = 7.5, 95% CI: 1.7–32.8). HTLV-I infection is associated with a variety of clinical manifestations, which may occur in patients who have not developed myelopathy. |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/15949 |
Data do documento: | 2007 |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivo | Descrição | Tamanho | Formato | |
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aid%2E2006%2E0140.pdf | 118,07 kB | Adobe PDF | Visualizar/Abrir |
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