Campo DC | Valor | Idioma |
dc.contributor.author | Poetker, Shelene K. W. | - |
dc.contributor.author | Porto, Maria Aurélia da Fonseca | - |
dc.contributor.author | Giozza, Silvana P. | - |
dc.contributor.author | Muniz, André Luís Nunes | - |
dc.contributor.author | Caskey, Marina F. | - |
dc.contributor.author | Carvalho Filho, Edgar Marcelino de | - |
dc.contributor.author | Glesby, Marshall J. | - |
dc.creator | Poetker, Shelene K. W. | - |
dc.creator | Porto, Maria Aurélia da Fonseca | - |
dc.creator | Giozza, Silvana P. | - |
dc.creator | Muniz, André Luís Nunes | - |
dc.creator | Caskey, Marina F. | - |
dc.creator | Carvalho Filho, Edgar Marcelino de | - |
dc.creator | Glesby, Marshall J. | - |
dc.date.accessioned | 2014-11-14T13:15:34Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1386-6532 | - |
dc.identifier.uri | http://repositorio.ufba.br/ri/handle/ri/16603 | - |
dc.description | Texto completo: acesso restrito. p. 54–58 | pt_BR |
dc.description.abstract | Background: Human T-lymphotropic virus type 1 (HTLV-1) is known to cause HTLV-associated myelopathy (HAM)/tropical spastic paraparesis and adult T cell leukemia. A growing body of evidence links HTLV-1 infection with an increasing spectrum of disease, including uveitis, periodontal disease, arthropathy, sicca syndrome, and neurologic deficits. Objectives: Despite recent findings, the natural history of HTLV-1 infection remains poorly defined. This study was designed to better characterize initial clinical and neurological findings in individuals diagnosed with HTLV-1 infection. Study design: We conducted a cross-sectional study of 71 individuals recently diagnosed with HTLV-1 and 71 uninfected age- and sex-matched blood donors in Salvador, Brazil. Subjects were administered a standardized questionnaire and underwent physical exam. Results: HTLV-1 infected subjects were significantly more likely than controls to report complaints of hand and foot numbness (OR = 5.3; 95% CI: 1.8–15.3; p = 0.002 and OR = 4.0; 95% CI: 1.3–12; p = 0.013 respectively), difficulty running (OR = 4.0; 95% CI: 1.1–14.2; p = 0.032), nocturia (OR = 5.0; 95% CI: 1.1–22.8; p = 0.038), arthralgia (OR = 3.3; 95% CI: 1.4–7.7; p = 0.006), and photophobia (OR = 3.3; 95% CI: 1.4–7.7; p = 0.006). Conclusions: Neurologic, ocular and rheumatologic complaints may be the first manifestations of HTLV-1 infection. Therefore, all patients presenting with initial diagnosis should be rigorously screened for these symptoms. | pt_BR |
dc.language.iso | en | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.source | http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.jcv.2011.02.004 | pt_BR |
dc.subject | HTLV-1 | pt_BR |
dc.subject | Neurologic manifestations | pt_BR |
dc.subject | Clinical manifestations | pt_BR |
dc.subject | Neuropathy | pt_BR |
dc.subject | Natural history | pt_BR |
dc.title | Clinical manifestations in individuals with recent diagnosis of HTLV type I infection | pt_BR |
dc.title.alternative | Journal of Clinical Virology | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 51, n. 1 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina)
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