https://repositorio.ufba.br/handle/ri/19051
Tipo: | Artigo de Periódico |
Título: | Heterogenic colonization patterns by Leptospira interrogans in Rattus norvegicus from urban slums. |
Título(s) alternativo(s): | Braz. J. Microbiol. |
Autor(es): | Santos, Ana Amélia Nunes Figueira, Cláudio Pereira Reis, Mitermayer Galvão dos Costa, Federico Ristow, Paula Carvalhal Lage von Buettner |
Autor(es): | Santos, Ana Amélia Nunes Figueira, Cláudio Pereira Reis, Mitermayer Galvão dos Costa, Federico Ristow, Paula Carvalhal Lage von Buettner |
Abstract: | We evaluated the renal colonization by Leptospira interrogans in Rattus norvegicus (rats), as it is the major natural reservoir of urban leptospirosis. We caught 72 R. norvegicus, out of which 32 were found to be positive for L. interrogans by immunofluorescence assay. From these rats, we selected 17 and divided them into six groups based on the mass-age/sex. We performed the immunohistochemistry test against L. interrogans in the kidney sections of the rats and systematically counted the colonized tubules (CTs) in 20 fields. The proportion of positive fields varied from 5% to 95%. The number of CTs in 20 fields varied from 0.5 to 85.5. These differences were not related to age or sex of the animals. The characterization of leptospiral colonization patterns in the natural reservoirs is important to better understand the host-pathogen interactions in leptospirosis. |
Palavras-chave: | Leptospira interrogans Renal colonization Natural reservoirs Rattus norvegicus |
País: | Brasil |
Editora / Evento / Instituição: | Sociedade Brasileira de Microbiologia |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/19051 |
Data do documento: | 2015 |
Aparece nas coleções: | Artigo Publicado em Periódico Nacional (ISC) |
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