O papel da ecocardiografia na amiloidose cardíaca

Abstract

Cardiac amyloidosis is an infiltrative disease caused by extracellular deposition of amyloid proteins in the myocardium, affecting cardiac structure and function. Diagnosing this condition can be challenging due to its nonspecific clinical presentation. Echocardiography plays a crucial role as a diagnostic and prognostic tool in cardiac amyloidosis, particularly through identifying characteristic findings such as ventricular thickening, specific strain deformation patterns, and diastolic dysfunction. This study discusses echocardiographic findings associated with the disease, based on nacional and international guidelines, including those from the European Society of Cardiology (ESC) and the American Heart Association (AHA), SBC (2021), BSE (2023) as well as recent studies such as the ATTR-ACT; the APOLLO-B (Maurer et al., 2023) and works by Gillmore et al. and Lane et al., by Kottam et al. (2023), by Merlini (2023).