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dc.creatorMacêdo, Beatriz Bastos-
dc.date.accessioned2025-03-31T14:36:09Z-
dc.date.available2025-03-31T14:36:09Z-
dc.date.issued2024-12-20-
dc.identifier.citationMACÊDO, Beatriz Bastos. Avaliação do volume condilar em pacientes com e sem sinais tomográficos de doença articular degenerativa. Orientadora: Patrícia Miranda Leite Ribeiro; Coorientador: João Frank Carvalho Dantas de Oliveira. 2024. 73 f. Dissertação (Mestrado em Processos Interativos dos Órgãos e Sistemas) - Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, 2024.pt_BR
dc.identifier.urihttps://repositorio.ufba.br/handle/ri/41636-
dc.description.abstractThe temporomandibular dysfunction (TMD) comprehends various pathological conditions affecting the temporomandibular joint (TMJ), and degenerative joint disease (DJD) is the most severe presentation. Dysfunction and intense pain characterize DJD. This study evaluated and compared the condylar volume of patients with and without DJD. An observational and retrospective study was conducted using computed tomography (CT) scans from the Radiology Department of FO/UFBA. NemoFAB Surgery 3D v.20.10.0 software analyzed 220 multislice CT scans performed between 2023 and 2024. The study included 188 participants with a mean age of 46 years and excluded 32. The comparison between patients with and without tomographic signs of DJD showed statistically significant differences in condylar volumes. The right condyle volume (RCV) was lower in patients with alterations (p = 0.005), as well as the left condyle volume (LCV) (p = 0.007). However, left and right condylar volumes did not statistically differ (p = 0.713). As for sex, women presented lower condylar volume on both sides, with RCV (p = 0.011) and LCV (p = 0.008), while men had higher condylar volumes. The Intraclass Correlation Coefficient of the measurements was 0.985 (p < 0.001), indicating excellent result reliability. Hence, this study demonstrates an association between the disease and lower mandibular condyle volume. Women exhibited lower condylar volumes on both sides, suggesting higher susceptibility to the impact of DJD. Right and left condylar volumes did not statistically differ, although the left side showed a higher prevalence of imaging alterations, aligning with previous literature findings.pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal da Bahiapt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectArticulação temporomandibularpt_BR
dc.subjectCôndilo mandibularpt_BR
dc.subjectDor facialpt_BR
dc.subjectOsteoartritept_BR
dc.subjectDoença crônicapt_BR
dc.subject.otherTemporomandibular Jointpt_BR
dc.subject.otherMandibular condylept_BR
dc.subject.otherFacial painpt_BR
dc.subject.otherOsteoarthritispt_BR
dc.subject.otherChronic diseasept_BR
dc.titleAvaliação do volume condilar em pacientes com e sem sinais tomográficos de doença articular degenerativapt_BR
dc.title.alternativeCondylar volume assessment in patients with and without degenerative joint diseasept_BR
dc.typeDissertaçãopt_BR
dc.publisher.programPrograma de Pós-Graduação em Processos Interativos dos Órgãos e Sistemas (PPGORGSISTEM) pt_BR
dc.publisher.initialsUFBApt_BR
dc.publisher.countryBrasilpt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIApt_BR
dc.contributor.advisor1Ribeiro, Patrícia Miranda Leite-
dc.contributor.advisor-co1Oliveira, João Frank Carvalho Dantas de-
dc.contributor.referee1Ribeiro, Patricia Miranda Leite-
dc.contributor.referee1IDhttps://orcid.org/0000-0002-4243-6887pt_BR
dc.contributor.referee1Latteshttp://lattes.cnpq.br/1291478815901411pt_BR
dc.contributor.referee2Souza, Raphael Freitas de-
dc.contributor.referee2IDhttps://orcid.org/0000-0001-8437-9991pt_BR
dc.contributor.referee2Latteshttp://lattes.cnpq.br/7092555880664311pt_BR
dc.contributor.referee3Oliveira, João Frank Carvalho Dantas de-
dc.contributor.referee3IDhttps://orcid.org/0000-0002-7643-5671pt_BR
dc.contributor.referee3Latteshttp://lattes.cnpq.br/0295298822772243pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/0056580989998486pt_BR
dc.description.resumoA disfunção temporomandibular (DTM) abrange uma variedade de condições patológicas que afeta a articulação temporomandibular (ATM), e a doença articular degenerativa (DAD) é sua apresentação mais severa. A DAD é caracterizada por disfunção e dor intensa. O objetivo do trabalho é avaliar e comparar o volume condilar de pacientes com e sem DAD. Foi realizado um estudo observacional e retrospectivo, utilizando-se tomografias computadorizadas (TC) da disciplina de Radiologia da FO/UFBA. Foram utilizadas 220 TC multislice, realizadas entre o período de 2023 e 2024. As imagens foram analisadas através do software NemoFAB Surgery 3D v.20.10.0. O estudo incluiu 188 participantes, com idade média de 46 anos, e 32 foram excluídos. Quando comparados pacientes com e sem sinais tomográficos de DAD, foram observadas diferenças estatísticas significativas nos volumes condilares. No côndilo direito, o volume (MVD) foi menor nos pacientes com alterações (p = 0,005). No côndilo esquerdo, o volume (MVE) também foi menor (p = 0,007). Entretanto, ao comparar os volumes condilares entre os lados esquerdo e direito, não houve diferença estatística (p = 0,713). Em relação ao sexo, as mulheres apresentaram menor volume condilar em ambos os lados, com MVD (p = 0,011) e MVE (p = 0,008), enquanto os homens apresentaram volumes condilares maiores. Por fim, o coeficiente de correlação intraclasse das medidas foi de 0,985 (p < 0,001), indicando excelente confiabilidade nos resultados obtidos. Com base nesses resultados, este estudo demonstra uma associação da doença com menor volume dos côndilos mandibulares. As mulheres apresentaram volumes condilares menores em ambos os lados, indicando maior suscetibilidade ao impacto da DAD. Não foram observadas diferenças estatísticas nos volumes condilares entre os lados direito e esquerdo, embora o lado esquerdo tenha apresentado maior prevalência de alterações imaginológicas, alinhando-se a achados prévios da literatura.pt_BR
dc.publisher.departmentInstituto de Ciências da Saúde - ICSpt_BR
dc.relation.referencesABRAMOFF, B.; CALDERA, F. E. Osteoarthritis: pathology, diagnosis, and treatment options. Medical Clinics of North America, Estados Unidos, v. 104, n. 2, p. 293–311, 2020. DOI: https://doi.org/10.1016/j.mcna.2019.10.007. ABUBAKER, A. O.; RASLAN, W. F.; SOTEREANOS, G. C. Estrogen and progesterone receptors in temporomandibular joint discs of symptomatic and asymptomatic persons: a preliminary study. Journal of Oral and Maxillofacial Surgery, Estados Unidos, v. 51, n. 10, p. 1096–1100, 1993. DOI: https://doi.org/10.1016/S0278-2391(10)80448-3. AHMAD, M.; SCHIFFMAN, E. L. Temporomandibular joint disorders and orofacial pain. Dental Clinics of North America, v. 60, p. 105–124, 2016. DOI: https://doi.org/10.1016/j.cden.2015.08.004. ALAM, M. K. et al. A 3D cone beam computed tomography (CBCT) investigation of mandibular condyle morphometry: gender determination, disparities, asymmetry assessment and relationship with mandibular size. Saudi Dent J, Arabia Saudita, v. 33, n. 7, p. 687–692, 2021. DOI: https://doi.org/10.1016/j.sdentj.2020.04.008. ALEXIOU, K. E.; STAMATAKIS, H. C.; TSIKLAKIS, K. Evaluation of the severity of temporomandibular joint osteoarthritic changes related to age using cone beam computed tomography. Dentomaxillofacial Radiology, Germany, v. 38, n. 3, p. 141–147, 2009. DOI: https://doi.org/10.1259/dmfr/59263880. BATIFOL, D. et al. Effect of intra-articular botulinum toxin injections on temporomandibular joint pain. Journal of Stomatology, Oral and Maxillofacial Surgery, França, v. 119, n. 4, p. 319–324, 2018. DOI: https://doi.org/10.1016/j.jormas.2018.06.002. BERGER, M. et al. Association between estrogen levels and temporomandibular disorders: a systematic literature review. Przeglad Menopauzalny, Poznan, v. 14, n. 4, p. 260–270, 2015. DOI: https://doi.org/10.5114/pm.2015.56538. BIELAJEW, B. J. et al. Knee orthopedics as a template for the temporomandibular joint. Cell Reports Medicine, Cambridge, v. 2, n. 5, 2021. DOI: https://doi.org/10.1016/j.xcrm.2021.100241. BIELECKI‐KOWALSKI, B.; KOZAKIEWICZ, M. Assessment of differences in the dimensions of mandible condyle models in fan‐ versus cone‐beam computer tomography acquisition. Materials, Basel, v. 14, n. 6, 2021. DOI: https://doi.org/10.3390/ma14061388. CARDONEANU, A. et al. Temporomandibular joint osteoarthritis: pathogenic mechanisms involving the cartilage and subchondral bone, and potential therapeutic strategies for joint regeneration. International Journal of Molecular Sciences, Switzerland, v. 24, p. 171, 2023. DOI: https://doi.org/10.3390/ijms24010171. 59 COVERT, L.; MATER, H. V.; HECHLER, B. L. Comprehensive management of rheumatic diseases affecting the temporomandibular joint. Diagnostics, Basel, v. 11, n. 3, p. 409, 2021. DOI: https://doi.org/10.3390/diagnostics. DADGAR-YEGANEH, A.; HATCHER, D. C.; OBEROI, S. Association between degenerative temporomandibular joint disorders, vertical facial growth, and airway dimension. J. World Fed. Orthod., Estados Unidos, v. 10, n. 1, p. 20–28, 2021. DOI: https://doi.org/10.1016/j.ejwf.2021.01.001. DA-SILVA, B. M. et al. Relationship between symptoms and imagenological signs of degenerative temporomandibular joint disorders using the Research Diagnostic Criteria for Temporomandibular Disorders and cone-beam computed tomography. Brazilian Journal of Pain, São Paulo, v. 3, n. 3, 2020. DOI: https://doi.org/10.5935/2595-0118.20200045. DE SOUSA, B. M. et al. Different treatments in patients with temporomandibular joint disorders: a comparative randomized study. Medicina (Lithuania), v. 56, n. 3, 2020. DOI: https://doi.org/10.3390/medicina56030113. DHABALE, G. S.; BHOWATE, R. R. Cone-beam computed tomography for temporomandibular joint imaging. Cureus, [s.l], v. 14, n. 11, p. e31515, 2022. DOI: https://doi.org/10.7759/cureus.31515. DUBNER, R.; OHRBACH, R.; DWORKIN, S. F. The evolution of TMD diagnosis: past, present, future. Journal of Dental Research, [s.l], v. 95, n. 10, p. 1093–1101, 2016. DOI: https://doi.org/10.1177/0022034516653922. DYGAS, S.; SZARMACH, I.; RADEJ, I. Assessment of the morphology and degenerative changes in the temporomandibular joint using CBCT according to the orthodontic approach: a scoping review. BioMed Research International, New York, v. 2022, p. 6863014, 2022. DOI: https://doi.org/10.1155/2022/6863014. GÖRÜRGÖZ, C. et al. Degenerative changes of the mandibular condyle in relation to the temporomandibular joint space, gender and age: a multicenter CBCT study. Dentistry and Medical Problems, Poland, v. 60, n. 1, p. 127–135, 2023. DOI: https://doi.org/10.17219/dmp/147514. GUNSON, J. M.; ARNETT, W. G. Condylar resorption, matrix metalloproteinases, and tetracyclines. RWISO Journal, p. 37–44, 2010. HATCHER, D. C. Anatomy of the mandible, temporomandibular joint, and dentition. Neuroimaging Clinics of North America, Estados unidos, v. 32, n. 4, p. 749-761, 2022. DOI: https://doi.org/10.1016/j.nic.2022.07.009. HORN, D. de S. G. et al. Hipoplasia condilar de provável origem otológica. Revista CEFAC, São Paulo, v. 18, n. 3, p. 801–806, 2016. DOI: https://doi.org/10.1590/19820216201618320215. ISHIBASHI, H. et al. Age-related changes in the human mandibular condyle: A morphologic, radiologic, and histologic study. Journal of Oral and Maxillofacial Surgery, Estados Unidos, v. 53, p. 1016–1023, 1995. 60 KANG, J. H. Associations among temporomandibular joint osteoarthritis, airway dimensions, and head and neck posture. Journal of Oral and Maxillofacial Surgery, Estados Unidos, v. 78, n. 12, p. 2183.e1, 2020. DOI: https://doi.org/10.1016/j.joms.2020.08.006. KAPOS, F. P. et al. Temporomandibular disorders: a review of current concepts in aetiology, diagnosis and management. Oral Surgery, [s.l], v. 13, n. 4, p. 321–334, 2020. DOI: https://doi.org/10.1111/ors.12473. KAYIPMAZ, S. et al. Trabecular structural changes in the mandibular condyle caused by degenerative osteoarthritis: a comparative study by cone-beam computed tomography imaging. Oral Radiology, [s.l], v. 35, n. 1, p. 51-58, 2019. DOI: https://doi.org/10.1007/s11282-018-0324-1. KOO, T. K.; LI, M. Y. A guideline of selecting and reporting intraclass correlation coefficients for reliability research. Journal of Chiropractic Medicine, Estados Unidos, v. 15, n. 2, p. 155–163, 2016. DOI: https://doi.org/10.1016/j.jcm.2016.02.012. LARHEIM, T. A. et al. Temporomandibular joint diagnostics using CBCT. Dentomaxillofacial Radiology, Germany, v. 44, p. 20140235, 2014. DOI: https://doi.org/10.1259/dmfr.20140235. LECHUGA, L.; WEIDLICH, G. A. Cone Beam CT vs. Fan Beam CT: A Comparison of Image Quality and Dose Delivered Between Two Differing CT Imaging Modalities. Cureus, [s.l], v.8, n.9, p.e778, 2016 DOI: https://doi.org/10.7759/cureus.778. LEI, J. et al. Condylar repair and regeneration in adolescents/young adults with early-stage degenerative temporomandibular joint disease: a randomised controlled study. Journal of Oral Rehabilitation, Oxford, v. 46, n. 8, p. 704–714, 2019. DOI: https://doi.org/10.1111/joor.12805. LI, C.-X. et al. Morphologic analysis of condyle among different disc status in the temporomandibular joints by three-dimensional reconstructive imaging: a preliminary study. BMC Oral Health, London, v. 22, n. 1, p. 395, 2022. DOI: https://doi.org/10.1186/s12903022-02438-1. LU, K. et al. Molecular signaling in temporomandibular joint osteoarthritis. Journal of Orthopaedic Translation, Singapore, v. 32, p. 21–27, 2022. DOI: https://doi.org/10.1016/j.jot.2021.07.001. MAGLIONE, H. O.; LUBERTI, R. F. Consideraciones clínicas e imagenológicas de la osteoartrosis en la articulación temporomandibular. Revista Círculo Argentino de Odontología, Buenos Aires, v. 77, n. 227, p. 13–17, 2018. MANI, F. M.; SIVASUBRAMANIAN, S. S. A study of temporomandibular joint osteoarthritis using computed tomographic imaging. Biomedicine Journal, Estados Unidos, v. 39, n. 3, p. 201–206, 2016. DOI: https://doi.org/10.1016/j.bj.2016.06.003. MELCHIOR, M. de O.; MAZZETTO, M. O.; MAGRI, L. V. Relation of painful TMD with the speech function: What are the possible characteristics of mandibular movements and the 61 main symptoms reported? CODAS, São Paulo, v. 31, n. 2, 2019. DOI: https://doi.org/10.1590/2317-1782/20182018161. MURPHY, M. K. et al. Temporomandibular joint disorders: a review of etiology, clinical management, and tissue engineering strategies HHS Public Access. International Journal of Oral and Maxillofacial Implants, v. 28, n. 6, p. e393–e414, 2013. DOI: https://doi.org/10.11607/jomi.te20. NASCIMENTO, G. C. et al. Temporomandibular inflammation regulates the matrix metalloproteinases MMP-2 and MMP-9 in limbic structures. Journal of Cellular Physiology, Estados Unidos, v. 236, n. 9, p. 6571–6580, 2021. DOI: https://doi.org/10.1002/jcp.30341. OZTURK, E. M. A.; ARTAS, A. Three-Dimensional Analysis of Age and Eichner IndexRelated Volumetric Changes in Mandibular Condyles. Cumhuriyet Dental Journal, Turkey, v. 27, n. 4, p. 194–200, 2024. DOI: https://doi.org/10.7126/cumudj.1473635. RAHMAN, K. K. et al. Detection and severity assessment of temporomandibular joint osteoarthritic changes in patients with temporomandibular disorders using CBCT. Erbil Dental Journal, Iraq, v. 7, n. 2, p. 132–143, 2024. DOI: https://doi.org/10.15218/edj.2024.15. ROMERO-REYES, M.; BASSIUR, J. P. Temporomandibular disorders, bruxism and headaches. Neurologic Clinics, [s,l.], v. 42, n. 2, p. 573–584, 2024. DOI: https://doi.org/10.1016/j.ncl.2023.12.010. SAMBATARO, S. et al. TMJ dysfunctions, systemic implications, and postural assessments: a review of recent literature. Journal of Functional Morphology and Kinesiology, Switzerland, v. 4, n. 3, p. 58, 2019. DOI: https://doi.org/10.3390/jfmk4030058. SCHIFFMAN, E. et al. Diagnostic criteria for temporomandibular disorders (DC/TMD) for clinical and research applications: recommendations of the International RDC/TMD Consortium Network* and Orofacial Pain Special Interest Group†. Journal of Oral and Facial Pain and Headache, Estados Unidos, v. 28, n. 1, p. 6–27, 2014. DOI: https://doi.org/10.11607/jop.1151. SCHIFFMAN, E.; OHRBACH, R. Executive summary of the diagnostic criteria for temporomandibular disorders for clinical and research applications. Journal of the American Dental Association, Chicago, v. 147, n. 6, p. 438-445, 2016. DOI: https://doi.org/10.1016/j.adaj.2016.01.007. SEEMAN, E. Perspective from density to structure: growing up and growing old on the surfaces of bone. Journal of Bone and Mineral Research, New York, v. 12, n. 4, p. 509520, 1997. DOI: 10.1359/jbmr.1997.12.4.509. SHETTY, R. S. et al. Analysis of the volumetric asymmetry of the mandibular condyles using CBCT. International Dental Journal, London, v. 72, n. 6, p. 797–804, 2022. DOI: https://doi.org/10.1016/j.identj.2022.06.019. SILVA, R. de C. P. et al. Aplicações clínicas da tomografia computadorizada cone beam na endodontia: revisão de literatura. Research, Society and Development, São Paulo, v. 11, n. 1, p. e21211124895, 2022. DOI: https://doi.org/10.33448/rsd-v11i1.24895. 62 SOTO, C. R. S.; FUENZALIDA R. M. M-W.; MENDEZ, C. R. Frequency of bone signs of osteoarthritis in the temporomandibular joint in a Chilean adult population using CBCT, during 2021-2022. International Journal of Odontostomatology, Recife, v. 17, n. 4, 2023. STEINBAUM, S. et al. Assessment of Condylar Changes in Patients with Degenerative Joint Disease of the TMJ After Stabilizing Splint Therapy: A Retrospective CBCT Study. Diagnostics, v.14, p.2331, 2024. DOI: 10.3390/diagnostics14202331 TAMIMI, D.; JALALI, E.; HATCHER, D. Temporomandibular joint imaging. Radiologic Clinics of North America, Estados Unidos, v. 56, p. 157–175, 2018. DOI: https://doi.org/10.1016/j.rcl.2017.08.011. VASEGH, Z. et al. Assessment of bony changes in temporomandibular joint in patients using cone beam computed tomography – a cross sectional study. Head and Face Medicine, [s.l], v. 19, n. 1, 2023. DOI: https://doi.org/10.1186/s13005-023-00392-z. VÎRLAN, M. J. R. et al. Degenerative bony changes in the temporal component of the temporomandibular joint – review of the literature. Romanian Journal of Morphology and Embryology, Romania, v. 63, p. 61–69, 2022. DOI: https://doi.org/10.47162/RJME.63.1.06. WALEWSKI, L. Â. et al. Cone beam computed tomography study of osteoarthritic alterations in the osseous components of temporomandibular joints in asymptomatic patients according to skeletal pattern, gender, and age. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Estados Unidos, v. 128, n. 1, p. 70-77, 2019. DOI: https://doi.org/10.1016/j.oooo.2019.01.072. WIECKIEWICZ, M. et al. Reported concepts for the treatment modalities and pain management of temporomandibular disorders. Journal of Headache and Pain, Milano, v. 16, p. 1–12, 2015. DOI: https://doi.org/10.1186/s10194-015-0586-5. WU, Y. et al. Combination of estrogen deficiency and excessive mechanical stress aggravates temporomandibular joint osteoarthritis in vivo. Archives of Oral Biology, Oxfors, v. 102, p. 39-46, 2019. DOI: https://doi.org/10.1016/j.archoralbio.2019.03.012.pt_BR
dc.type.degreeMestrado Acadêmicopt_BR
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