Campo DC | Valor | Idioma |
dc.contributor.author | Teixeira, M. C. A. | - |
dc.contributor.author | Inês, Elizabete de Jesus | - |
dc.contributor.author | Pacheco, Flávia Thamiris Figueiredo | - |
dc.contributor.author | Silva, R. K. N. R. | - |
dc.contributor.author | Mendes, A. V. | - |
dc.contributor.author | Adorno, Elisângela Vitória | - |
dc.contributor.author | Lima, F. M. | - |
dc.contributor.author | Soares, N. M. | - |
dc.creator | Teixeira, M. C. A. | - |
dc.creator | Inês, Elizabete de Jesus | - |
dc.creator | Pacheco, Flávia Thamiris Figueiredo | - |
dc.creator | Silva, R. K. N. R. | - |
dc.creator | Mendes, A. V. | - |
dc.creator | Adorno, Elisângela Vitória | - |
dc.creator | Lima, F. M. | - |
dc.creator | Soares, N. M. | - |
dc.date.accessioned | 2012-04-19T17:47:20Z | - |
dc.date.available | 2012-04-19T17:47:20Z | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 0022-3395 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/5672 | - |
dc.description | p. 833-835. | pt_BR |
dc.description.abstract | Strongyloides stercoralis infection is endemic in many tropical and subtropical areas. The parasite has the unusual ability to multiply inside the host due to the transformation of rhabditiform larvae
into infective filariforms. Several studies have shown that chronic alcoholism is an important factor that predisposes to strongyloidiasis. The increased susceptibility to S. stercoralis infections seen in alcoholic individuals could be explained by their increased exposure to the parasite, malnutrition, breakdown of local immune responses, and/or alterations in
intestinal barriers. Moreover, ethanol intoxication can elevate human
endogenous corticosterone, which, in turn, suppresses T cell function and increases the fecundity and survival of the parasite, mimicking the effect of worm ecdysteroides. Although chronic alcoholism is a risk factor for nematode infection, most cases of hyperinfection or dissemination are
associated with the presence of hepatic cirrhosis or strongyloidiasis-related
symptoms. The present study describes a case of S. stercoralis hyperinfection in a 51-yr-old male patient without gastrointestinal or pulmonary symptoms and with previous anemia and chronic alcoholism.
He was not receiving glucocorticoid therapy and tested negative for HTLV and human immunodeficiency virus (HIV), but he had a history of alcohol addiction for more than 20 yr. Laboratory test results showed increased eosinophilia and a high immunoglobulin E (IgE) level, which may have
temporarily protected the patient from dissemination of infection, but not
prevented proliferation of the parasite, as shown by the large number of S.
stercoralis larvae recovered using the Baermann method. Evaluation for
strongyloidiasis should occur in alcoholics, especially in endemic areas, to
prevent occult asymptomatic infections from progressing to life-threatening
cases. | pt_BR |
dc.language.iso | en | pt_BR |
dc.source | DOI: 10.1645/GE-2358.1 | pt_BR |
dc.title | Asymptomatic Strongyloides stercoralis Hyperinfection in an alcoholic patient with intense anemia | pt_BR |
dc.title.alternative | Journal of Parasitology | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 96, n. 4 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina)
|