Campo DC | Valor | Idioma |
dc.contributor.author | Lyra, André Castro | - |
dc.contributor.author | Pinho, João Renato Rebello | - |
dc.contributor.author | Silva, L.K. | - |
dc.contributor.author | Sousa, L. | - |
dc.contributor.author | Saraceni, C. P. | - |
dc.contributor.author | Braga, Eduardo Lorens | - |
dc.contributor.author | Pereira, J. E. | - |
dc.contributor.author | Zarife, Maria Alice Sant'anna | - |
dc.contributor.author | Lyra, Luiz Guilherme Costa | - |
dc.creator | Lyra, André Castro | - |
dc.creator | Pinho, João Renato Rebello | - |
dc.creator | Silva, L.K. | - |
dc.creator | Sousa, L. | - |
dc.creator | Saraceni, C. P. | - |
dc.creator | Braga, Eduardo Lorens | - |
dc.creator | Pereira, J. E. | - |
dc.creator | Zarife, Maria Alice Sant'anna | - |
dc.creator | Lyra, Luiz Guilherme Costa | - |
dc.date.accessioned | 2012-07-30T19:51:39Z | - |
dc.date.available | 2012-07-30T19:51:39Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0100-879X | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/6508 | - |
dc.description | p. 767-775 | pt_BR |
dc.description.abstract | he aim of the present study was to evaluate the prevalence of HEV, TTV and GBV-C/GBV-C/HGV in patients with acute viral hepatitis A, B and non-A-C. We evaluated sera of 94 patients from a sentinel program who had acute hepatitis A (N = 40), B (N = 42) and non-A-C (N = 12); 71 blood donors served as controls. IgM and anti-HEV IgG antibodies were detected by enzyme immunoassay using commercial kits. TTV and GBV-C/HGV were detected by nested PCR; genotyping was done by sequencing and phylogenetic analysis. Anti-HEV IgG was present in 38, 10 and 17% of patients with hepatitis A, B and non-A-C. Four patients with hepatitis A and 1 with non-A-C hepatitis also had anti-HEV IgM detected in serum. TTV was detected in 21% of patients with acute hepatitis and in 31% of donors. GBV-C/HGV was detected in 9% of patients with hepatitis, and in 10% of donors. We found TTV isolates of genotypes 1, 2, 3, and 4 and GBV-C/HGV isolates of genotypes 1 and 2. Mean aminotransferase levels were lower in patients who were TTV or GBV-C/HGV positive. In conclusion, the detection of anti-HEV IgM in some acute hepatitis A cases suggests co-infection with HEV and hepatitis E could be the etiology of a few cases of sporadic non-A-C hepatitis in Salvador, Brazil. TTV genotype 1, 2, 3 and 4 isolates and GBV-C/HGV genotype 1 and 2 strains are frequent in the studied population. TTV and GBV-C/HGV infection does not appear to have a role in the etiology of acute hepatitis. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Scielo | pt_BR |
dc.source | http://dx.doi.org/10.1590/S0100-879X2005000500015 | pt_BR |
dc.subject | Acute hepatitis | pt_BR |
dc.subject | Hepatitis E | pt_BR |
dc.subject | TTV | pt_BR |
dc.subject | GBV-C/HGV | pt_BR |
dc.subject | Genotype | pt_BR |
dc.subject | Brazil | pt_BR |
dc.title | HEV, TTV and GBV-C/HGV markers in patients with acute viral hepatitis | pt_BR |
dc.title.alternative | Brazilian Journal of Medical and Biological Research | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 38, n. 5 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina)
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