https://repositorio.ufba.br/handle/ri/8320
Campo DC | Valor | Idioma |
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dc.contributor.author | Silva, E. de Castro e | - |
dc.contributor.author | Sarmento, Clarissa | - |
dc.contributor.author | Nascimento, T. A. | - |
dc.contributor.author | Luz, C. P. | - |
dc.contributor.author | Soares, T. | - |
dc.contributor.author | Marinho, C. A. | - |
dc.contributor.author | Cunha, M. | - |
dc.contributor.author | Bulcão, C. | - |
dc.contributor.author | Oliveira, I. R. de | - |
dc.contributor.author | Fregoneze, J. B. | - |
dc.creator | Silva, E. de Castro e | - |
dc.creator | Sarmento, Clarissa | - |
dc.creator | Nascimento, T. A. | - |
dc.creator | Luz, C. P. | - |
dc.creator | Soares, T. | - |
dc.creator | Marinho, C. A. | - |
dc.creator | Cunha, M. | - |
dc.creator | Bulcão, C. | - |
dc.creator | Oliveira, I. R. de | - |
dc.creator | Fregoneze, J. B. | - |
dc.date.accessioned | 2013-02-01T11:57:25Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 0091-3057 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/8320 | - |
dc.description | Texto completo: acesso restrito. p.749–754 | pt_BR |
dc.description.abstract | DE CASTRO-E-SILVA, E., C. SARMENTO, T. A. NASCIMENTO, C. P. LUZ, T. SOARES, C. A. MARINHO, M. CUNHA, C. BULCÃO, I. R. DE OLIVEIRA AND J. B. FREGONEZE. Effect of third ventricle administration of L-694,247, a selective 5-HT1D receptor agonist, on water intake in rats. PHARMACOL BIOCHEM BEHAV 57[4]749–754, 1997.—L-694,247, a selective 5-HT1D receptor agonist, injected directly into the third ventricle (2.5, 5.0, and 10.0 μg/rat) of dehydrated rats induced a dose-dependent partial blockade of water intake. Injected in this way, the compound abolishes drinking behavior induced by third ventricle administration of carbachol (2 μg/rat), angiotensin II (5 ng/rat), and isoproterenol (40 μg/rat). In addition, intraventricular injections of L-694,247 did not modify water intake in normohydrated rats. The effects of L-694,247 are due to a specific interaction with 5-HT1D receptors, because its inhibitory effect on water intake in dehydrated rats is blocked by the previous administration of a 5-HT1D antagonist, GR 127935 (5 μg/rat), directly into the third ventricle. It is concluded that central 5-HT1D receptor activation disrupts the functional integrity of central pathways related to drinking behavior. | pt_BR |
dc.language.iso | en | pt_BR |
dc.source | http://dx.doi.org/10.1016/S0091-3057(96)00457-1 | pt_BR |
dc.subject | 5-HT1D receptors | pt_BR |
dc.subject | Serotonin | pt_BR |
dc.subject | Angiotensin II | pt_BR |
dc.subject | Adrenoceptors | pt_BR |
dc.subject | Cholinergic receptors | pt_BR |
dc.subject | Drinking behavior | pt_BR |
dc.title | Effect of third ventricle administration of L-694,247, a selective 5-HT1(D) receptor agonist, on water intake in rats | pt_BR |
dc.title.alternative | Pharmacology Biochemistry and Behavior | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 57, n. 4 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (ICS) |
Arquivo | Descrição | Tamanho | Formato | |
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-SILVA.pdf Restricted Access | 246,9 kB | Adobe PDF | Visualizar/Abrir Solicitar uma cópia |
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